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lung tissue microarray analysis pdf


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Microarray analysis in pulmonary hypertension- lung tissue microarray analysis pdf ,November 2015), species (human), technology (microarray or gene array) and disease (group 1 and 3 PH or PAH). A short synopsis of rodent PH model microarray studies is provided at the end of this review. Microarray studies on human lung tissue Explanted lungs (representing the end-stage disease) or biopsy material (representing a point in timeMicroarray Analysis of Long Non-Coding RNAs in Lung ...Oct 09, 2020·Lung Tissue Samples. ... In summary, our study revealed the differential expression level of lncRNAs between COPD and non-COPD lung tissues through microarray analysis. GO and pathway analyses could help us explore and predict the function of certain lncRNAs. The results also suggested that HOXA-AS2 promotes cell proliferation and …



Tissue microarrays – automated analysis and future ...

Tissue microarrays have rapidly become a vital tool in the analysis of protein biomarkers on large patient cohorts. Composed of hundreds of miniature histologic tissue cores taken from patient tumors and arrayed in a grid pattern, tissue microarrays have great potential for …

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In vitro evaluation of nanoplastics using human lung ...

Dec 15, 2021·In the present study, we employed human lung epithelial cells, microarray analysis and co-culture model to determine the potential risk of PS-NPs in developing adverse pulmonary effects. The results of the study suggest that airborne nanoplastics can be easily inhaled into the lung, induce oxidative stress and inflammatory responses, followed ...

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Microarray-based Analysis of Ventilator-induced Lung Injury

Microarray-based Analysis of Ventilator-induced Lung Injury Mark M. Wurfel Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, Washington ... lung tissue as the source of RNA confounds the interpretation of these findings (and findings from several subsequent studies)

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(PDF) Tissue Microarray Analysis of EGFR Copy Number ...

A normal number of EGFR. signals is found in 122 carcinomas (78.7%), and copy number changes of EGFR were. established in 33 (21.3%) of all …

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DNA Microarrays and Cancer - University of Rochester

microarray and analyze the results to determine which patients might benefit most from chemotherapy. • Part 6: Microarrays and Cancer Diagnosis (20 minutes) This data analysis activity illustrates how microarrays can be used in cancer diagnosis. The DNA Microarrays (Gene Chips) activities introduce (or reinforce) the following

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DNA Microarrays and Cancer - University of Rochester

microarray and analyze the results to determine which patients might benefit most from chemotherapy. • Part 6: Microarrays and Cancer Diagnosis (20 minutes) This data analysis activity illustrates how microarrays can be used in cancer diagnosis. The DNA Microarrays (Gene Chips) activities introduce (or reinforce) the following

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Analysis of Microarray-Identified Genes and MicroRNAs ...

Human Genome Microarray platform. The data were derived from lung tissue samples from 40 IPF patients and 8 healthy controls. The GSE10667 dataset was generated by the University of Pittsburgh using the GPL4133 Agilent-014850 Whole Human Genome Microarray platform. The data were derived from 23 IPF and 15 control lung tissue samples (Table 1). 3.2.

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(PDF) Discriminative microarray analysis ... - Academia.edu

Download Free PDF. Download Free PDF ... Discriminative microarray analysis reveals a global reprogramming of transcriptional profile in the human lung adenocarcinoma and predicts diagnostic and prognostic biomarkers. ... analysis and feature selection in paired samples impacts the identification of the genes essential for reprogramming lung ...

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Immunohistochemical Analysis of Tissue Microarrays ...

Jul 21, 2010·Abstract. Immunohistochemistry (IHC) is the gold standard methodology for in-situ protein expression analysis in tissue samples. The combination of IHC and tissue microarray (TMA) technology allows for the simultaneous analysis of hundreds of tissue samples with an unprecedented degree of experimental standardization.

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Microarray analysis of long non-coding RNAs in COPD lung ...

Microarray analysis of long non-coding RNAs in COPD lung tissue Inflamm Res. 2015 Feb;64(2):119-26. doi: 10.1007/s00011-014-0790-9. ... In this study, we provide the description of genome-wide lncRNA expression in the lung tissue of non-smokers without Chronic obstructive pulmonary disease (COPD), of smokers without COPD and of smokers with ...

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MG Chromosomal Microarray Analysis - EmblemHealth

Oct 12, 2018·81229 Cytogenomic constitutional (genome-wide) microarray analysis; interrogation of genomic regions for copy number and single nucleotide polymorphism (SNP) variants for chromosomal abnormalities 81405 Molecular pathology procedure, Level 6 (eg, analysis of 6-10 exons by DNA sequence analysis, mutation

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(PDF) Microarray Analysis of Gene Expression in the ...

Microarray Analysis of Gene Expression in the Embryonic Lung* . × ... Microarray Analysis of Gene Expression in the Embryonic Lung<xref rid="AFF1"><sup>*</sup></xref> CHEST Journal, 2002. Suizhen Lin. Download Download PDF. Full PDF Package Download Full PDF Package. This Paper. A short summary of this paper. 37 Full PDFs related to this paper.

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Transcriptome Analysis Reveals Differential Splicing ...

Transcriptome Analysis Reveals Differential Splicing Events in IPF Lung Tissue Tracy Nance1*, Kevin S. Smith1, Vanessa Anaya1, Rhea Richardson1, Lawrence Ho2, Mauro Pala1, Sara Mostafavi3, Alexis Battle3, Carol Feghali-Bostwick4, Glenn Rosen5*, Stephen B. Montgomery1* 1Department of Pathology, Stanford University, Stanford, California, United …

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Immunohistochemical prognostic factors in resected ...

Immunohistochemical prognostic factors in resected colorectal lung metastases using tissue microarray analysis Eur J Surg Oncol . 2006 Apr;32(3):308-9. doi: 10.1016/j.ejso.2005.12.003.

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(PDF) Lung Gene Expression Analysis (LGEA): an integrative ...

Users can compare the expression data from major types of analyses using the extended database: (1) single- distinct mouse strains and different technical platforms includ- cell transcriptome analysis using ‘LungGENS’ (2) sorted lung ing RNA microarray and RNA-seq. Dynamic profile patterns are cell populations analysis using ...

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Analysis of Microarray-Identified Genes and MicroRNAs ...

Human Genome Microarray platform. The data were derived from lung tissue samples from 40 IPF patients and 8 healthy controls. The GSE10667 dataset was generated by the University of Pittsburgh using the GPL4133 Agilent-014850 Whole Human Genome Microarray platform. The data were derived from 23 IPF and 15 control lung tissue samples (Table 1). 3.2.

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Tissue Microarrays in Non–Small-Cell Lung Cancer ...

May 01, 2014·Tissue microarray (TMA) technology, originally described by Battifora and refined by Kononen, has become a potentially powerful technology for high-throughput analysis of protein expression in a large number of tissue samples.1, 2 Hundreds of tissue cores can be arranged on a single slide, depending on the core size, and simultaneously analyzed ...

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Tissue microarray analysis of Fas and FasL expressions in ...

Tissue microarray analysis of Fas and FasL expressions in human non-small cell lung carcinomas; with reference to the p53 and bcl-2 overexpressions J Korean Med Sci . 2005 Oct;20(5):770-6. doi: 10.3346/jkms.2005.20.5.770.

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Microarray analysis of long non-coding RNAs in COPD …

Microarray analysis identified a large number of differentially expressed lncRNAs in relation to CS exposure in mouse [137] and human lung tissue [138], but …

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Large-scale molecular and tissue microarray analysis of ...

Jun 01, 2003·Tissue microarrays containing 1 to 3 0.6-mm cores from 621 different zinc formalin-fixed, paraffin-embedded cancers were constructed using a tissue microarrayer (Beecher Instruments, Silver Spring, MD). In addition, whole tissue sections from paraffin blocks of 15 adenocarcinomas of the lung, 10 of which were papillary carcinomas,19 were …

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Tissue Microarray - an overview | ScienceDirect Topics

Tissue microarrays (TMAs) (tissue arrays or tissue chips) were originally described by Wan et al. in 1987. 16 TMAs are produced by relocating hundreds or thousands of representative tissue cores from multiple conventional histologic paraffin blocks. These tissue cores can be arranged on a single slide or block (Figure 18).TMA is a powerful technology for high-throughput …

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MG Chromosomal Microarray Analysis - EmblemHealth

Oct 12, 2018·81229 Cytogenomic constitutional (genome-wide) microarray analysis; interrogation of genomic regions for copy number and single nucleotide polymorphism (SNP) variants for chromosomal abnormalities 81405 Molecular pathology procedure, Level 6 (eg, analysis of 6-10 exons by DNA sequence analysis, mutation

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Tissue microarray: Current perspectives in pathology

Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 2001; 10: 657-662. 4. Moch H, Schraml P, Bubendorf L, Mirlacher M, Kononen J, Gasser T, Mihatsch MJ, Kallioniemi OP, Sauter G.High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma.

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(PDF) Identification of genes differentially over ...

squamous tumors tested. Expression of L525S in Figure 2 Microarray analysis of potential lung squamous tumor antigens. (a) Shows genes that are squamous tissue speci®c as these genes are also expressed in normal squamous cell containing tissues such as skin (probe pair 1).

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