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adipose tissue metabolism


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Human adipose dynamics and metabolic health- adipose tissue metabolism ,The two types of adipose tissue in humans, white and brown, have distinct developmental origins and functions. Human white adipose tissue plays a pivotal role in maintaining whole-body energy homeostasis by storing triglycerides when energy is in surplus, ...Replication of SARS-CoV-2 in adipose tissue determines ...Dec 10, 2021·Fatty acids released by adipose tissue include exogenous ones originally derived from the diet and such originating from endogenous synthesis. The latter metabolic pathway, termed de novo lipogenesis (DNL), is highly active in adipose tissue and is regulated mainly at the transcriptional level. Notably, the N-terminal non-structural protein 1 ...



Adipose Tissue Remodeling: Its Role in Energy Metabolism ...

Apr 13, 2016·The adipose tissue is a central metabolic organ in the regulation of whole-body energy homeostasis. The white adipose tissue functions as a key energy reservoir for other organs, whereas the brown adipose tissue accumulates lipids for cold-induced adaptive thermogenesis. Adipose tissues secrete various hormones, cytokines, and metabolites …

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Adipose Tissue: Physiology to Metabolic Dysfunction ...

Adipose Tissue in the Regulation of Lipid Metabolism. Adipose tissue stores body fat as neutral TAGs and represents the chief energy reservoir within mammals. Although many diverse cell types are found in whole AT, adipocytes constitute the largest cell volumes and are the defining AT cell type.

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Adipose tissue inflammation and metabolic dysfunction in ...

Jul 30, 2020·WHITE ADIPOSE TISSUE White adipose tissue (WAT) is the major fat-storing depot and also serves as the largest endocrine organ to secrete adi-pokinesand cytokines systemically. Adipokinesare involved in various metabolic and physiological signaling cascades and regulateinsulin signaling, glucose uptake,fatty acidoxi-

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The adipose tissue metabolism: role of testosterone and ...

Jul 24, 2000·The adipose tissue metabolism: role of testosterone and dehydroepiandrosterone G De Pergola 1 International Journal of Obesity volume 24 , pages S59–S63 ( 2000 ) Cite this article

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Adipose Tissue Metabolism | SpringerLink

Past anatomists thought of fat cells as ‘empty cells’, the lipid being lost in fixation of the tissue, and attitudes to adipose tissue and its functions have till recently reflected this description. Adipose tissue was originally thought by physiologists to function only as an insulator and to give to the human body bouyancy in water.

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Adipose Tissue: What Is It, Location, Function, and More ...

Adipose tissue is a specialized type of connective tissue that arises from the differentiation of mesenchymal stem cells into adipocytes during fetal development. Mesenchymal stem cells are pluripotent cells that can transform into various cell types, including fat cells, bone cells, cartilage cells, and muscle cells, among others.

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Adipose and Metabolic Tissue Study Group Seminar Series ...

Adipose and Metabolic Tissue Study Group Seminar Series. Sponsored by the Adipose Tissue Biology and Nutrient Metabolism (ABM) Core and Enrichment Program of the Boston Nutrition Obesity Research Center. Adipose Seminar Series 2021-2022. VIRTUAL March 22, 2022 “Listening in on human-microbiome metabolic dialogues in diabetes and metabolic ...

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Adipose tissue in control of metabolism - Peeref

A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function (2016) Katrin J. Svensson et al. Cell Metabolism Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans (2016 ...

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Adipose tissue and lipid metabolism - IJS

on adipose cell biology, this chapter will focus on the biochemistry of triacylglycerol metabolism. 2. Adipose development 2.1. Development of white and brown adipose tissue in vivo The study of white adipose tissue (WAT) development in mammals has been facilitated by the use of experimental animal models.

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Adipose tissue in control of metabolism - PubMed

Adipose tissue in control of metabolism Adipose tissue plays a central role in regulating whole-body energy and glucose homeostasis through its subtle functions at both organ and systemic levels. On one hand, adipose tissue stores energy in the form of lipid and controls the lipid mobilization and distribution in the body. On the other ha …

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Human adipose dynamics and metabolic health

The two types of adipose tissue in humans, white and brown, have distinct developmental origins and functions. Human white adipose tissue plays a pivotal role in maintaining whole-body energy homeostasis by storing triglycerides when energy is in surplus, ...

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New Obesity Tool? - Harvard Medical School

Apr 14, 2021·Brown fat, or brown adipose tissue, is a distinct type of fat that is activated in response to cold temperatures. Its primary role is to produce heat to help maintain body temperature, and it achieves that by burning calories.

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Sirtuins in Adipose Tissue Metabolism | IntechOpen

Oct 31, 2017·The relevance of sirtuins in adipose tissue development and metabolism and their effects on metabolism of glucose and lipids primarily in the liver, and insulin function suggest a possible link between sirtuins and obesity. The level of expression and activity of SIRT1 decrease in adipose tissue in different obesity models.

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Regulation of lipid metabolism in adipose tissue ...

Feb 28, 2007·Adipose tissue is a major source of metabolic fuel. This metabolic fuel is stored in the form of triacylglycerol. Lipolysis of triacylglycerol yields …

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Adipose Tissue Inflammation and Metabolic Dysfunction in ...

Adipose tissue-derived stem cells (ADSCs) have received widespread attention, which provides new ideas for the treatment of obesity and various metabolic-related diseases, due …

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Energy metabolism in brown adipose tissue - Wang - 2021 ...

May 24, 2021·Glucose is the most common carbohydrate, and 18 F-FDG-PET shows active glucose metabolism in human BAT. While adipose tissue is also known as fat-storing tissue, it is not surprising that fats (lipids) serve as an energy source in BAT. BAT utilizes both intracellular and extracellular lipids as the fuel for thermogenesis.

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Adipose tissue - Wikipedia

Adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages.Adipose tissue is derived from preadipocytes.

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Regional Differences in Adipose Tissue Metabolism in Women ...

May 01, 2006·Excess accumulation of adipose tissue within the abdominal cavity, or visceral obesity, has been associated with a cluster of metabolic alterations, which includes insulin resistance, hyperinsulinemia, elevated triglyceride levels, low HDL cholesterol, and hypertension as its main features (1,2).In many instances, the association between visceral adipose tissue …

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Replication of SARS-CoV-2 in adipose tissue determines ...

Dec 10, 2021·Fatty acids released by adipose tissue include exogenous ones originally derived from the diet and such originating from endogenous synthesis. The latter metabolic pathway, termed de novo lipogenesis (DNL), is highly active in adipose tissue and is regulated mainly at the transcriptional level. Notably, the N-terminal non-structural protein 1 ...

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Sirtuins in Adipose Tissue Metabolism | IntechOpen

Oct 31, 2017·The relevance of sirtuins in adipose tissue development and metabolism and their effects on metabolism of glucose and lipids primarily in the liver, and insulin function suggest a possible link between sirtuins and obesity. The level of expression and activity of SIRT1 decrease in adipose tissue in different obesity models.

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Human white adipose tissue: A highly dynamic metabolic ...

Dec 16, 2021·Adipose lipid turnover is also decreased in insulin resistance and certain forms of dyslipidemia. Altogether, adult human adipose tissue is in a highly dynamic state. Alterations in the turnover of fat cells and their lipids are therefore novel factors to consider in the pathophysiology of common metabolic disorders.

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Adipose tissue in control of metabolism - Peeref

A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function (2016) Katrin J. Svensson et al. Cell Metabolism Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans (2016 ...

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Adipose tissue in control of metabolism

counteract obesity. Therefore, adipose tissue dysfunction plays a prominent role in the development of obesity and its related disorders such as insulin resistance, cardiovascular disease, diabetes, depression and cancer. In this review, we will summarize the recent findings of adipose tissue in the control of metabolism,

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Adipose tissue inflammation in glucose metabolism ...

Sep 19, 2013·Adipose tissue was formally considered an inert depository for excess calories in the form of lipids. It is, however, now known that the WAT actively functions as an endocrine organ. Indeed, one of the first adipocyte derived hormones, leptin, was cloned in 1994 and found to be implicated in energy homeostasis [ 10 ].

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